A comparison of voice quality following radiotherapy or transoral laser microsurgery of T1a laryngeal carcinomas

Kinshuck, AJ ORCID: 0000-0003-4756-106X (2016) A comparison of voice quality following radiotherapy or transoral laser microsurgery of T1a laryngeal carcinomas Doctor of Medicine thesis, University of Liverpool.

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Abstract

Introduction: Patients with laryngeal carcinoma often present early due to the change in their voice. The treatment for T1aN0M0 carcinoma varies throughout the world, but whether radiotherapy (RT) or endolaryngeal laser excision is performed both result in excellent local control of the tumour and five year survival rates. There are advantages and disadvantages of either treatment but there are no appropriately powered randomised controlled trials comparing them. Over recent decades external beam RT has become the more popular choice and this is partly due to a perception of poor voice outcomes from surgical excision. However with the development of technology allowing surgical precision, transoral laser microsurgery (TLM) has resulted in low morbidity and good voice outcomes. Objective: This research has three main objectives: a. To describe acoustic parameters of ‘normal’ voice; b. To compare voice outcomes in patients treated with TLM with those treated with radiotherapy for T1a SCC of the glottis; c. To investigate longitudinal changes in voice quality in patients undergoing TLM for T1a SCC of the glottis. Methods: The research was divided into three main parts. The first part was to analyse the acoustic ... (continues)

Item Type:	Thesis (Doctor of Medicine)
Divisions:	Faculty of Health & Life Sciences
Depositing User:	Symplectic Admin
Date Deposited:	22 Dec 2016 08:15
Last Modified:	29 Oct 2024 18:07
DOI:	10.17638/03004620
Supervisors:	Jones, TM ORCID: 0000-0002-4058-6013 Shaw, R ORCID: 0000-0001-7027-8997
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3004620
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