Changes in Dietary Fat Intake and Projections for Coronary Heart Disease Mortality in Sweden: A Simulation Study

Bjorck, Lena, Rosengren, Annika, Winkvist, Anna, Capewell, Simon ORCID: 0000-0003-3960-8999, Adiels, Martin, Bandosz, Piotr ORCID: 0000-0002-6395-6216, Critchley, Julia, Boman, Kurt, Guzman-Castillo, Maria, O'Flaherty, Martin ORCID: 0000-0001-8944-4131
et al (show 1 more authors) (2016) Changes in Dietary Fat Intake and Projections for Coronary Heart Disease Mortality in Sweden: A Simulation Study. PLOS ONE, 11 (8). e0160474-.

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<h4>Objective</h4>In Sweden, previous favourable trends in blood cholesterol levels have recently levelled off or even increased in some age groups since 2003, potentially reflecting changing fashions and attitudes towards dietary saturated fatty acids (SFA). We aimed to examine the potential effect of different SFA intake on future coronary heart disease (CHD) mortality in 2025.<h4>Methods</h4>We compared the effect on future CHD mortality of two different scenarios for fat intake a) daily SFA intake decreasing to 10 energy percent (E%), and b) daily SFA intake rising to 20 E%. We assumed that there would be moderate improvements in smoking (5%), salt intake (1g/day) and physical inactivity (5% decrease) to continue recent, positive trends.<h4>Results</h4>In the baseline scenario which assumed that recent mortality declines continue, approximately 5,975 CHD deaths might occur in year 2025. Anticipated improvements in smoking, dietary salt intake and physical activity, would result in some 380 (-6.4%) fewer deaths (235 in men and 145 in women). In combination with a mean SFA daily intake of 10 E%, a total of 810 (-14%) fewer deaths would occur in 2025 (535 in men and 275 in women). If the overall consumption of SFA rose to 20 E%, the expected mortality decline would be wiped out and approximately 20 (0.3%) additional deaths might occur.<h4>Conclusion</h4>CHD mortality may increase as a result of unfavourable trends in diets rich in saturated fats resulting in increases in blood cholesterol levels. These could cancel out the favourable trends in salt intake, smoking and physical activity.

Item Type: Article
Uncontrolled Keywords: Humans, Coronary Disease, Sodium Chloride, Dietary, Cholesterol, Dietary Fats, Fatty Acids, Mortality, Risk Factors, Feeding Behavior, Smoking, Life Style, Models, Theoretical, Adult, Aged, Aged, 80 and over, Middle Aged, Sweden, Female, Male
Depositing User: Symplectic Admin
Date Deposited: 01 Dec 2016 11:08
Last Modified: 19 Jan 2023 07:24
DOI: 10.1371/journal.pone.0160474
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