Poulet, Blandine and Staines, Katherine A
(2016)
New developments in osteoarthritis and cartilage biology.
CURRENT OPINION IN PHARMACOLOGY, 28.
pp. 8-13.
Abstract
Osteoarthritis (OA) is a degenerative joint disease and the most common form of arthritis. Characterised by articular cartilage loss, subchondral bone thickening and osteophyte formation, the OA joint afflicts much pain and disability. Whilst OA has been associated with many contributing factors, its underpinning molecular mechanisms are, nevertheless, not fully understood. Clinical management of OA is largely palliative and there is an ever growing need for an effective disease modifying treatment. This review discusses some of the recent progress in OA therapies in the different joint tissues affected by OA pathology.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Cartilage, Articular, Animals, Humans, Osteoarthritis, Pain, Antirheumatic Agents, Drug Design, Osteophyte |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 13 Dec 2016 16:18 |
| Last Modified: | 19 Jan 2023 07:24 |
| DOI: | 10.1016/j.coph.2016.02.009 |
| Open Access URL: | http://dx.doi.org/10.1016/j.coph.2016.02.009 |
| Related URLs: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3004862 |
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