Liu, Yuxia, Wang, Chao, Xue, Dong, Xiao, Miao, Liu, Jiao, Li, Chaoqun and Xiao, Jianliang ORCID: 0000-0003-2010-247X
(2017)
Reactions Catalysed by a Binuclear Copper Complex: Relay Aerobic Oxidation of <i>N</i>-Aryl Tetrahydroisoquinolines to Dihydroisoquinolones with a Vitamin B1 Analogue.
CHEMISTRY-A EUROPEAN JOURNAL, 23 (13).
pp. 3062-3066.
Other
Text amide.DOCX - Author Accepted Manuscript Download (1MB) |
Abstract
N-Aryl tetrahydroisoquinolines were oxidised to dihydroisoquinolones through the relay catalysis of a binuclear paddle-wheel copper complex and a vitamin B1 analogue with oxygen as oxidant. Mechanistic studies revealed that the copper catalyst oxidises amines to the corresponding iminium salts, which are then oxygenated to lactam products by catalysis of the vitamin B1 analogue.
Item Type: | Article |
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Uncontrolled Keywords: | amides, copper, homogeneous catalysis, oxidation, relay catalysis |
Depositing User: | Symplectic Admin |
Date Deposited: | 09 Mar 2017 10:53 |
Last Modified: | 12 Oct 2023 09:51 |
DOI: | 10.1002/chem.201604750 |
Related URLs: | |
URI: | https://livrepository.liverpool.ac.uk/id/eprint/3006279 |