The evolving world of pseudoenzymes: proteins, prejudice and zombies

Eyers, Patrick A ORCID: 0000-0002-9220-2966 and Murphy, James M (2016) The evolving world of pseudoenzymes: proteins, prejudice and zombies. BMC BIOLOGY, 14 (1). 98-.

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Official URL: http://dx.doi.org/10.1186/s12915-016-0322-x

Abstract

Pseudoenzymes are catalytically deficient variants of enzymes that are represented in all major enzyme families. Their regulatory functions in signalling pathways are shedding new light on the non-catalytic functions of active enzymes, and are suggesting new ways to target cellular signalling mechanisms with drugs.

Item Type:	Article
Uncontrolled Keywords:	Enzymes, Proteins, Evolution, Molecular, Signal Transduction
Depositing User:	Symplectic Admin
Date Deposited:	06 Apr 2017 13:52
Last Modified:	19 Jan 2023 07:07
DOI:	10.1186/s12915-016-0322-x
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3006816