The evolving world of pseudoenzymes: proteins, prejudice and zombies



Eyers, Patrick A ORCID: 0000-0002-9220-2966 and Murphy, James M
(2016) The evolving world of pseudoenzymes: proteins, prejudice and zombies. BMC BIOLOGY, 14 (1). 98-. ISSN 1741-7007, 1741-7007

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Abstract

Pseudoenzymes are catalytically deficient variants of enzymes that are represented in all major enzyme families. Their regulatory functions in signalling pathways are shedding new light on the non-catalytic functions of active enzymes, and are suggesting new ways to target cellular signalling mechanisms with drugs.

Item Type: Article
Uncontrolled Keywords: Enzymes, Proteins, Evolution, Molecular, Signal Transduction
Depositing User: Symplectic Admin
Date Deposited: 06 Apr 2017 13:52
Last Modified: 07 Dec 2024 17:25
DOI: 10.1186/s12915-016-0322-x
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3006816