On the Regioselectivity of the Nickel-Catalyzed Insertion of Alkynes into the Carbon-Carbon Bond of Oxetan-3-one

Barday, Manuel, Janot, Christopher, Clare, Daniel, Carr-Knox, Caitlin, Higginson, Bradley, Ho, Kelvin YT and Aissa, Christophe ORCID: 0000-0003-0750-9435 (2017) On the Regioselectivity of the Nickel-Catalyzed Insertion of Alkynes into the Carbon-Carbon Bond of Oxetan-3-one. SYNTHESIS-STUTTGART, 49 (16). pp. 3582-3589.

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Official URL: http://dx.doi.org/10.1055/s-0036-1589052

Abstract

<jats:p>The study of the regioselectivity of insertion of unsymmetrical alkynes into the carbon–carbon bond of oxetan-3-one in the presence of a nickel catalyst has revealed a strong directing effect of a 2-thienyl substituent. This effect is larger than those of 2-vinylbenzene, trimethylsilyl, aryl, or 3-thienyl groups.</jats:p>

Item Type:	Article
Uncontrolled Keywords:	carbon-carbon bond activation, nickel, catalysis, oxeta-none, alkynes, regioselectivity, insertion, pyrans
Depositing User:	Symplectic Admin
Date Deposited:	29 Jun 2017 08:34
Last Modified:	19 Jan 2023 07:02
DOI:	10.1055/s-0036-1589052
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3008170