The continuous oxidation of HMF to FDCA and the immobilisation and stabilisation of periplasmic aldehyde oxidase (PaoABC)



McKenna, SM, Mines, P, Law, P, Kovacs-Schreiner, K, Birmingham, WR, Turner, NJ, Leimkuehler, S and Carnell, AJ ORCID: 0000-0002-6353-403X
(2017) The continuous oxidation of HMF to FDCA and the immobilisation and stabilisation of periplasmic aldehyde oxidase (PaoABC). GREEN CHEMISTRY, 19. 4660 - 4665.

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Abstract

By manipulating the reaction conditions, furandicarboxylic acid (FDCA) was prepared by the biooxidation of hydroxymethyl furfural (HMF) in a continuous one-pot reaction using galactose oxidase M3–5, periplasmic aldehyde oxidase (PaoABC), catalase and horseradish peroxidase. In addition, PaoABC was successfully entrapped in a SiO2 hydrogel and recycled 14 times without loss of activity. The catalyst was able to tolerate up to 200 mM DFF concentration giving FDCA in full conversion with very promising TOF and TON values.

Item Type: Article
Depositing User: Symplectic Admin
Date Deposited: 07 Sep 2017 06:29
Last Modified: 16 Oct 2021 03:10
DOI: 10.1039/c7gc01696d
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3009320