SPIONs for cell labelling and tracking using MRI: magnetite or maghemite?

Barrow, Michael, Taylor, Arthur ORCID: 0000-0003-2028-6694, Fuentes-Caparros, Ana M, Sharkey, Jack, Daniels, Luke M ORCID: 0000-0002-7077-6125, Mandal, Pranab, Park, B Kevin, Murray, Patricia ORCID: 0000-0003-1316-148X, Rosseinsky, Matthew J ORCID: 0000-0002-1910-2483 and Adams, Dave J (2017) SPIONs for cell labelling and tracking using MRI: magnetite or maghemite? BIOMATERIALS SCIENCE, 6 (1). pp. 101-106. ISSN 2047-4830, 2047-4849

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Abstract

Although there is extensive literature covering the biomedical applications of superparamagnetic iron oxide nanoparticles (SPIONs), the phase of the iron oxide core used is not often taken into account when cell labelling and tracking studies for regenerative medicine are considered. Here, we use a co-precipitation reaction to synthesise particles of both magnetite- (Fe<inf>3</inf>O<inf>4</inf>) and maghemite- (γ-Fe<inf>2</inf>O<inf>3</inf>) based cores and consider whether the extra synthesis step to make maghemite based particles is advantageous for cell tracking.

Item Type:	Article
Uncontrolled Keywords:	Ferric Compounds, Contrast Media, Magnetic Resonance Imaging, Magnetite Nanoparticles
Depositing User:	Symplectic Admin
Date Deposited:	28 Nov 2017 10:37
Last Modified:	16 Jun 2026 16:33
DOI:	10.1039/c7bm00515f
Related Websites:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3012823
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