Chronic Lymphocytic Leukaemia/ Small-Cell Lymphocytic Lymphoma of the Lacrimal Sac: A Case Series.



Krishna, Yamini, Irion, Luciane D, Karim, Sozan, Dharmsena, Aruna, McCormick, Austin and Coupland, Sarah E ORCID: 0000-0002-1464-2069
(2017) Chronic Lymphocytic Leukaemia/ Small-Cell Lymphocytic Lymphoma of the Lacrimal Sac: A Case Series. Ocular oncology and pathology, 3 (3). 224 - 228.

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Abstract

<h4>Background</h4>Lymphomas of the lacrimal sac are rare, accounting for less than 10% of lacrimal sac malignant tumours. They may present with symptoms typical of secondary acquired nasolacrimal duct obstruction and are thus often misdiagnosed.<h4>Methods</h4>Case series and literature review.<h4>Results</h4>Herein we describe 3 cases of chronic lymphocytic leukaemia (CLL)/small-cell lymphocytic lymphoma (SLL) of the lacrimal sac with immunohistochemical and in 1 case molecular confirmation.<h4>Conclusion</h4>Lymphomas of the lacrimal sac should be suspected in patients with known CLL presenting with epiphora and dacryocystitis. During dacryocystorhinostomy, an incisional biopsy of the lacrimal sac is essential for confirming CLL/SLL involvement and may guide treatment.

Item Type: Article
Depositing User: Symplectic Admin
Date Deposited: 16 Apr 2019 14:52
Last Modified: 15 Oct 2021 12:03
DOI: 10.1159/000455148
URI: https://livrepository.liverpool.ac.uk/id/eprint/3023094