Multi-ethnic genome-wide association study for atrial fibrillation



Roselli, Carolina, Chaffin, Mark D, Weng, Lu-Chen, Aeschbacher, Stefanie, Ahlberg, Gustav, Albert, Christine M, Almgren, Peter, Alonso, Alvaro, Anderson, Christopher D, Aragam, Krishna G
et al (show 208 more authors) (2018) Multi-ethnic genome-wide association study for atrial fibrillation. NATURE GENETICS, 50 (9). 1225 - +.

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Broad_AF_main_text_03_08_2018.pdf - Accepted Version

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Broad_AF_supplement_03_08_2018.pdf - Accepted Version

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Broad_AF_integrated_supplementary_figures_03_08_2018.doc - Accepted Version

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Figure 1. Study and analysis flowchart.ps - Accepted Version

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Figure 2. Manhattan plot of combined-ancestry meta-analysis.ai - Accepted Version

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Figure 3. Volcano plot of transcriptome-wide analysis from human heart tissues.ps - Accepted Version

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Figure 4. Cross-trait associations of AF risk variants with AF risk factors in the UK Biobank.ai - Accepted Version

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Supplementary Table 3. Known loci in combined ancestry meta-analysis.xlsx - Accepted Version

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Supplementary Table 4. Gene set enrichment analysis results for combined ancestry meta-analysis.xlsx - Accepted Version

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Supplementary Table 5. Novel and known loci in ancestry specific meta-analyses.xlsx - Accepted Version

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Supplementary Table 7. Loci with multiple signals identified by conditional and joint analysis for European ancestry meta-analysis.xlsx - Accepted Version

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Supplementary Table 9. Chromatin states for sentinel variants and proxies from Roadmap Epigenomics across all tissues and heart.xlsx - Accepted Version

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Supplementary Table 11. Significant cis-eQTLs for sentinel variants from combined ancestry meta-analysis in GTEx heart tissues.xlsx - Accepted Version

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Supplementary Table 11. Significant cis-eQTLs for sentinel variants from combined ancestry meta-analysis in GTEx heart tissues.xlsx - Accepted Version

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Supplementary Table 12. Probable AF susceptibility genes for loci from combined ancestry meta-analysis.xlsx - Accepted Version

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Supplementary Table 13. Transcriptome-wide results based on summary level data from combined ancestry meta-analysis.xlsx - Accepted Version

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Supplementary Table 14. Association to diseases and traits in NHGRI-EBI GWAS catalog for sentinel variants or proxies from combined ancestry meta-analysis.xlsx - Accepted Version

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Supplementary Table 15. PheWAS results in UK Biobank for sentinel variants from combined ancestry meta-analysis.xlsx - Accepted Version

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Supplementary Table 16. 134 loci associated with atrial fibrillation.xlsx - Accepted Version

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Supplementary Table 17. Baseline summary for GWAS.xlsx - Accepted Version

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Supplementary Table 18. GWAS summary on genotyping, QC, imputation and analysis per study.xlsx - Accepted Version

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Item Type: Article
Depositing User: Symplectic Admin
Date Deposited: 13 Aug 2018 08:33
Last Modified: 05 Dec 2019 01:10
DOI: 10.1038/s41588-018-0133-9
Related URLs:
URI: http://livrepository.liverpool.ac.uk/id/eprint/3024835
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