Straatmann, VS, Taylor-Robinson, DC 
ORCID: 0000-0002-5828-7724, Bergh, EH and Fleming, KM
(2018)
ALCOHOL CONSUMPTION IN PREGNANCY AND CHILDHOOD HEARING AND NEURODEVELOPMENTAL PROBLEMS IN THE UK: ANALYSIS FROM THE MILLENNIUM COHORT STUDY
In: Oral presentations, 2018-9-6 - ?.
Abstract
Background Fetal Alcohol Spectrum Disorders (FASD) is the leading preventable cause of disability in children in the UK. Identification and diagnosis of FASD is poor, with many children receiving diagnoses of other neurodevelopmental deficit (including Attention Deficit Hyperactivity Disorder -ADHD), but no FASD diagnosis. FASD is associated with a large number of comorbid conditions, including an 80-fold increased risk of sensorineural hearing loss. Using a contemporary UK birth cohort we examined the association between maternal alcohol consumption in pregnancy, hearing problems at age 3 and later ADHD.Methods Analysis of the UK Millennium Cohort Study (MCS), based on 9179 children participating in 3 survey sweeps (9 months, 3, 7 years old). The main outcome was parental-reported hearing problems, at age 3. We also examined self-reported diagnosis of ADHD at age 7. Incident rate ratios (IRRs; 95% confidence intervals [CI]) were estimated using Poisson regression, according to maternal drinking in pregnancy in units per week (categorised as none, 1–7, 8–14 and 15 or more) adjusted for measures of childhood socioeconomic conditions. Analyses were conducted using Stata/SE with svy commands to account for the sampling design and attrition.Results At age 3, 1328 children (14.4%) had reported a hearing problem with the most common of these being otitis media and unspecified hearing loss. Children of mothers who reported drinking 15 or more units per week of alcohol in pregnancy were twice as likely to have hearing problems compared to mothers who reported never drinking in pregnancy (aIRR1.9(95% CI[1.07, 3.39])). Risk of ADHD diagnosis at age 7 was also elevated in children of mothers who drank 15 or more units per week though this was not statistically significant at the 5% level (aIRR2.79(95% CI[0.91, 8.57])). Children with hearing problems at age 3 were 3.5 times more likely to have a diagnosis of ADHD at age 7 (aIRR3.49(95% CI[1.92, 6.32])).
| Item Type: | Conference Item (Unspecified) |
|---|---|
| Uncontrolled Keywords: | 4201 Allied Health and Rehabilitation Science, 42 Health Sciences, Substance Misuse, Mental Health, Behavioral and Social Science, Perinatal Period - Conditions Originating in Perinatal Period, Attention Deficit Hyperactivity Disorder (ADHD), Intellectual and Developmental Disabilities (IDD), Fetal Alcohol Spectrum Disorders (FASD), Hearing Loss, Health Disparities and Racial or Ethnic Minority Health Research, Conditions Affecting the Embryonic and Fetal Periods, Neurosciences, Brain Disorders, Women's Health, Alcoholism, Alcohol Use and Health, Pediatric Research Initiative, Clinical Research, Pregnancy, 2.3 Psychological, social and economic factors, Ear, 3 Good Health and Well Being |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 19 Oct 2018 09:55 |
| Last Modified: | 22 May 2026 21:37 |
| DOI: | 10.1136/jech-2018-SSMabstracts.54 |
| Open Access URL: | https://jech.bmj.com/content/72/Suppl_1/A26.3 |
| Related Websites: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3027526 |
| Disclaimer: | The University of Liverpool is not responsible for content contained on other websites from links within repository metadata. Please contact us if you notice anything that appears incorrect or inappropriate. |
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