Stevens, Andrew, Yang, Hao, Hao, Weituo, Jones, Lewys, Ophus, Colin, Nellist, Peter D and Browning, Nigel D
(2018)
Subsampled STEM-ptychography.
APPLIED PHYSICS LETTERS, 113 (3).
033104-.
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Abstract
<jats:p>Ptychography has been shown to be an efficient phase contrast imaging technique for scanning transmission electron microscopes (STEM). STEM-ptychography uses a fast pixelated detector to collect a “4-dimensional” dataset consisting of a 2D electron diffraction pattern at every probe position of a 2D raster-scan. This 4D dataset can be used to recover the phase-image. Current camera technology, unfortunately, can only achieve a frame rate of a few thousand detector frames-per-second (fps), which means that the acquisition time of the 4D dataset is up to 1000× slower than the scanning speed in a conventional STEM, thereby limiting the potential applications of this method for dose-fragile and dynamic specimens. In this letter, we demonstrate that subsampling provides an effective method for optimizing ptychographic acquisition by reducing both the number of detector-pixels and the number of probe positions. Subsampling and recovery of the 4D dataset are shown using an experimental 4D dataset with randomly removed detector-pixels and probe positions. After compressive sensing recovery, Wigner distribution deconvolution is applied to obtain phase-images. Randomly sampling both the probe positions and the detector at 10% gives sufficient information for phase-retrieval and reduces acquisition time by 100×, thereby making STEM-ptychography competitive with conventional STEM.</jats:p>
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | 51 Physical Sciences, Bioengineering, Stem Cell Research - Nonembryonic - Non-Human, Stem Cell Research |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 15 Nov 2018 09:31 |
| Last Modified: | 21 Jun 2024 08:49 |
| DOI: | 10.1063/1.5040496 |
| Related URLs: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3028844 |
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