Characterisation of the NRF2 transcriptional network and its response to chemical insult in primary human hepatocytes: implications for prediction of drug-induced liver injury



Copple, Ian M ORCID: 0000-0003-4101-1913, den Hollander, Wouter, Callegaro, Giulia, Mutter, Fiona E, Maggs, James L, Schofield, Amy L, Rainbow, Lucille ORCID: 0000-0003-0447-6885, Fang, Yongxiang ORCID: 0000-0002-4514-5292, Sutherland, Jeffrey J, Ellis, Ewa C
et al (show 6 more authors) (2019) Characterisation of the NRF2 transcriptional network and its response to chemical insult in primary human hepatocytes: implications for prediction of drug-induced liver injury. ARCHIVES OF TOXICOLOGY, 93 (2). 385 - 399.

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Item Type: Article
Uncontrolled Keywords: DILI, NFE2L2, KEAP1, WGCNA, Oxidative stress
Depositing User: Symplectic Admin
Date Deposited: 23 Nov 2018 16:15
Last Modified: 27 May 2020 10:08
DOI: 10.1007/s00204-018-2354-1
Open Access URL: https://doi.org/10.1007/s00204-018-2354-1
Related URLs:
URI: http://livrepository.liverpool.ac.uk/id/eprint/3029044