Reduced habit-driven errors in Parkinson’s Disease

Bannard, Colin ORCID: 0000-0001-5579-5830, Leriche, Mariana, Bandmann, Oliver, Brown, Christopher, Ferracane, Elisa, Sanchez-Ferro, Alvaro, Obeso, Jose, Redgrave, Peter and Stafford, Tom
(2019) Reduced habit-driven errors in Parkinson’s Disease. Nature Scientific Reports, 9 (1). 3423-.

Access the full-text of this item by clicking on the Open Access link.
[img] Text
reduced-habit-driven-author-accepted-version.pdf - Author Accepted Manuscript

Download (596kB)


Parkinson’s Disease can be understood as a disorder of motor habits. A prediction of this theory is that early stage Parkinson’s patients will display fewer errors caused by interference from previously over-learned behaviours. We test this prediction in the domain of skilled typing, where actions are easy to record and errors easy to identify. We describe a method for categorizing errors as simple motor errors or habit-driven errors. We test Spanish and English participants with and without Parkinson’s, and show that indeed patients make fewer habit errors than healthy controls, and, further, that classification of error type increases the accuracy of discriminating between patients and healthy controls. As well as being a validation of a theory-led prediction, these results offer promise for automated, enhanced and early diagnosis of Parkinson’s Disease.

Item Type: Article
Uncontrolled Keywords: basal ganglia, human behaviour
Depositing User: Symplectic Admin
Date Deposited: 13 Dec 2018 09:13
Last Modified: 19 Jan 2023 01:09
DOI: 10.1038/s41598-019-39294-z
Open Access URL:
Related URLs: