Diagnosis and treatment of brain metastases from solid tumors: guidelines from the European Association of Neuro-Oncology (EANO)



Soffietti, Riccardo, Abacioglu, Ufuk, Baumert, Brigitta, Combs, Stephanie E, Kinhult, Sara, Kros, Johan M, Marosi, Christine, Metellus, Philippe, Radbruch, Alexander, Freixa, Salvador S Villa
et al (show 8 more authors) (2017) Diagnosis and treatment of brain metastases from solid tumors: guidelines from the European Association of Neuro-Oncology (EANO). NEURO-ONCOLOGY, 19 (2). pp. 162-174.

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Abstract

The management of patients with brain metastases has become a major issue due to the increasing frequency and complexity of the diagnostic and therapeutic approaches. In 2014, the European Association of Neuro-Oncology (EANO) created a multidisciplinary Task Force to draw evidence-based guidelines for patients with brain metastases from solid tumors. Here, we present these guidelines, which provide a consensus review of evidence and recommendations for diagnosis by neuroimaging and neuropathology, staging, prognostic factors, and different treatment options. Specifically, we addressed options such as surgery, stereotactic radiosurgery/stereotactic fractionated radiotherapy, whole-brain radiotherapy, chemotherapy and targeted therapy (with particular attention to brain metastases from non-small cell lung cancer, melanoma and breast and renal cancer), and supportive care.

Item Type: Article
Uncontrolled Keywords: brain metastases, chemotherapy, neuroimaging, neuropathology, stereotactic radiosurgery/ stereotactic fractionated radiotherapy, supportive care, surgery, targeted therapy, whole-brain radiation therapy
Depositing User: Symplectic Admin
Date Deposited: 25 Jan 2019 14:34
Last Modified: 19 Jan 2023 01:07
DOI: 10.1093/neuonc/now241
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3031045