Physical Rehabilitation Core Outcomes In Critical illness (PRACTICE): Protocol for development of a core outcome set


Connolly, B, Denehy, L, Hart, N, Pattison, N, Williamson, P ORCID: 0000-0001-9802-6636 and Blackwood, B (2018) Physical Rehabilitation Core Outcomes In Critical illness (PRACTICE): Protocol for development of a core outcome set Trials, 19 (1). 294-. ISSN 1745-6215, 1745-6215

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Abstract

Background: Existing data on physical rehabilitation interventions in critical illness are challenged by outcome heterogeneity that limits data synthesis and translation of research findings into clinical practice. This protocol describes the PRACTICE study to develop a core outcome set (COS) for trials of physical rehabilitation interventions delivered across the continuum of a patient's recovery from the intensive care unit until reintegration in the community following hospital discharge. Methods: Mixed methods will be used including: systematic reviews of quantitative and qualitative literature; qualitative interviews with patients and caregivers; a modified Delphi consensus process with researcher, clinician and patient/caregiver stakeholder groups; and consensus meetings for ratification of findings, resolving uncertainty, or developing an action plan for COS implementation. Discussion: The PRACTICE COS will inform relevant stakeholders about important outcomes regarding physical rehabilitation in critical illness, and may enhance the future design and conduct of trials in this area.

Item Type: Article
Uncontrolled Keywords: Physical rehabilitation, Core outcome set, Consensus, Critical illness, Outcome, Measurement
Depositing User: Symplectic Admin
Date Deposited: 28 Jan 2019 15:31
Last Modified: 01 Mar 2026 07:23
DOI: 10.1186/s13063-018-2678-4
Open Access URL: https://doi.org/10.1186/s13063-018-2678-4
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URI: https://livrepository.liverpool.ac.uk/id/eprint/3031913
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