Do Cryptic Reservoirs Threaten Gambiense-Sleeping Sickness Elimination?

Buscher, Philippe, Bart, Jean-Mathieu, Boelaert, Marleen, Bucheton, Bruno, Cecchi, Giuliano, Chitnis, Nakul, Courtin, David, Figueiredo, Luisa M, Franco, Jose-Ramon, Grebaut, Pascal
et al (show 18 more authors) (2018) Do Cryptic Reservoirs Threaten Gambiense-Sleeping Sickness Elimination? TRENDS IN PARASITOLOGY, 34 (3). pp. 197-207.

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Trypanosoma brucei gambiense causes human African trypanosomiasis (HAT). Between 1990 and 2015, almost 440000 cases were reported. Large-scale screening of populations at risk, drug donations, and efforts by national and international stakeholders have brought the epidemic under control with <2200 cases in 2016. The World Health Organization (WHO) has set the goals of gambiense-HAT elimination as a public health problem for 2020, and of interruption of transmission to humans for 2030. Latent human infections and possible animal reservoirs may challenge these goals. It remains largely unknown whether, and to what extend, they have an impact on gambiense-HAT transmission. We argue that a better understanding of the contribution of human and putative animal reservoirs to gambiense-HAT epidemiology is mandatory to inform elimination strategies.

Item Type: Article
Uncontrolled Keywords: Informal Expert Group on Gambiense HAT Reservoirs, Animals, Humans, Trypanosoma brucei gambiense, Trypanosomiasis, African, Risk Factors, Disease Reservoirs, Disease Eradication
Depositing User: Symplectic Admin
Date Deposited: 12 Feb 2019 10:20
Last Modified: 19 Jan 2023 01:04
DOI: 10.1016/
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