The neurological complications of chikungunya virus: A systematic review



Mehta, Ravi, Gerardin, Patrick, Antunes de Brito, Carlos Alexandre, Soares, Cristiane Nascimento, Brito Ferreira, Maria Lucia and Solomon, Tom ORCID: 0000-0001-7266-6547
(2018) The neurological complications of chikungunya virus: A systematic review. REVIEWS IN MEDICAL VIROLOGY, 28 (3). e1978-.

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Abstract

We performed a systematic review on the neurological complications of chikungunya virus. Such complications are being reported increasingly, owing primarily to the scale of recent epidemics but also to a growing understanding of the virus' neurovirulence. We performed a thorough literature search using PubMed and Scopus databases, summating the data on all published reports of neurological disease associated with chikungunya virus. We appraised the data for each major condition in adults, children, and neonates, as well as evaluating the latest evidence on disease pathogenesis and management strategies. The review provides a comprehensive summary for clinicians, public health officials, and researchers tackling the challenges associated with this important emerging pathogen.

Item Type: Article
Uncontrolled Keywords: acute disseminated encephalomyelitis, chikungunya, complications, congenital infections, encephalitis, Guillain-Barre syndrome, myelitis, neonatal infection, neurological, optic neuritis, retinitis, uveitis
Depositing User: Symplectic Admin
Date Deposited: 14 Feb 2019 11:58
Last Modified: 19 Jan 2023 01:03
DOI: 10.1002/rmv.1978
Open Access URL: http://doi.org/10.1002/rmv.1978
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URI: https://livrepository.liverpool.ac.uk/id/eprint/3032848