High-throughput SRCD using multi-well plates and its applications

Hussain, Rohanah, Javorfi, Tamas, Rudd, Timothy R ORCID: 0000-0003-4434-0333 and Siligardi, Giuliano (2016) High-throughput SRCD using multi-well plates and its applications. SCIENTIFIC REPORTS, 6 (1). 38028-. ISSN 2045-2322, 2045-2322

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Abstract

The sample compartment for high-throughput synchrotron radiation circular dichroism (HT-SRCD) has been developed to satisfy an increased demand of protein characterisation in terms of folding and binding interaction properties not only in the traditional field of structural biology but also in the growing research area of material science with the potential to save time by 80%. As the understanding of protein behaviour in different solvent environments has increased dramatically the development of novel functions such as recombinant proteins modified to have different functions from harvesting solar energy to metabolonics for cleaning heavy and metal and organic molecule pollutions, there is a need to characterise speedily these system.

Item Type:	Article
Uncontrolled Keywords:	Humans, Proteins, Circular Dichroism, Protein Folding, Synchrotrons
Depositing User:	Symplectic Admin
Date Deposited:	14 Feb 2019 15:18
Last Modified:	07 Dec 2024 20:13
DOI:	10.1038/srep38028
Open Access URL:	https://doi.org/10.1038/srep38028
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3032868