Rapid Detection of the Antibiotic Sulfamethazine in Pig Body Fluids by Paper Spray Mass Spectrometry



Suraritdechachai, Surased, Charoenpakdee, Chayan, Young, Iain ORCID: 0000-0002-9502-6216, Maher, Simon, Vilaivan, Tirayut and Praneenararat, Thanit
(2019) Rapid Detection of the Antibiotic Sulfamethazine in Pig Body Fluids by Paper Spray Mass Spectrometry. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 67 (10). pp. 3055-3061.

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Abstract

We report herein a practical method for nonlethal detection of the antibiotic sulfamethazine in pig body fluids via the combination of simple extraction and paper spray mass spectrometry (PS-MS). This method requires minimal sample preparation while still providing high sensitivities and accuracies in complex matrices including pig whole blood (LOD = 7.9 μg/L; recovery = 95.4-103.7%), pig serum (LOD = 11.5 μg/L; recovery = 103.2-106.2%), and synthetic urine (LOD = 11.2 μg/L; recovery = 99.1-103.2%). Given a known correlation between the level of sulfamethazine in body fluids and edible tissues, this method shows great promise as a practical and nonlethal solution for rapid testing of the drug, which can substantially aid managerial decision in the livestock industry.

Item Type: Article
Uncontrolled Keywords: paper spray, mass spectrometry, sulfamethazine, extraction, ambient ionization
Depositing User: Symplectic Admin
Date Deposited: 13 Mar 2019 12:31
Last Modified: 19 Jan 2023 00:57
DOI: 10.1021/acs.jafc.9b00500
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3034113