Singlet Oxygen Generation by Laser Irradiation of Gold Nanoparticles

Chadwick, SJ, Salah, D, Livesey, PM, Brust, M ORCID: 0000-0001-6301-7123 and Volk, M ORCID: 0000-0003-3555-8584 (2016) Singlet Oxygen Generation by Laser Irradiation of Gold Nanoparticles. Journal of Physical Chemistry C, 120 (19). pp. 10647-10657. ISSN 1932-7447, 1932-7455

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Abstract

The formation of singlet oxygen by irradiation of gold nanoparticles in their plasmon resonance band with continuous or pulsed laser light has been investigated. Citrate-stabilized nanoparticles were found to facilitate the photogeneration of singlet oxygen, albeit with low quantum yield. The reaction caused by pulsed laser irradiation makes use of the equilibrated hot electrons that can reach temperatures of several thousand degrees during the laser pulse. Although less efficient, continuous irradiation, which acts via the short-lived directly excited primary “hot” electrons only, can produce enough singlet oxygen for photodynamic cancer therapy and has significant advantages for practical applications. However, careful design of the nanoparticles is needed, since even a moderately thick capping layer can completely inhibit singlet oxygen formation. Moreover, the efficiency of the process also depends on the nanoparticle size.

Item Type:	Article
Uncontrolled Keywords:	34 Chemical Sciences, 3406 Physical Chemistry, Bioengineering, Nanotechnology
Depositing User:	Symplectic Admin
Date Deposited:	24 Apr 2019 13:55
Last Modified:	15 Aug 2025 01:45
DOI:	10.1021/acs.jpcc.6b02005
Open Access URL:	http://pubs.acs.org/doi/abs/10.1021/acs.jpcc.6b020...
Related Websites:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3038173

Available Versions of this Item

• Singlet Oxygen Generation by Laser Irradiation of Gold Nanoparticles. (deposited 09 May 2016 09:59)
  • Singlet Oxygen Generation by Laser Irradiation of Gold Nanoparticles. (deposited 27 May 2016 07:41)
    • Singlet Oxygen Generation by Laser Irradiation of Gold Nanoparticles. (deposited 24 Apr 2019 13:55) [Currently Displayed]