Learning from the STRIDER trial

Sharp, A ORCID: 0000-0003-3396-7464, Cornforth, C ORCID: 0000-0002-6047-8634 and Alfirevic, Z (2019) Learning from the STRIDER trial Obstetrics Gynaecology and Reproductive Medicine, 29 (8). pp. 240-241. ISSN 1751-7214, 1879-3622

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Abstract

The STRIDER is an international consortium of five randomised trials of the use of sildenafil to treat fetal growth restriction. We describe the scientific rationale and processes undertaken to take advantage of such a joint approach to studying new interventions in pregnancy. We also describe the challenges faced during recruitment and the further challenges faced after initial publication. We discuss concerns about fetal wellbeing identified in the Netherlands STRIDER trial and the implications of this on other studies and the wider maternity research community.

Item Type:	Article
Uncontrolled Keywords:	3215 Reproductive Medicine, 32 Biomedical and Clinical Sciences, Conditions Affecting the Embryonic and Fetal Periods, Infant Mortality, Pediatric Research Initiative, Clinical Research, Perinatal Period - Conditions Originating in Perinatal Period, Pregnancy, Clinical Trials and Supportive Activities, Reproductive health and childbirth, 3 Good Health and Well Being
Depositing User:	Symplectic Admin
Date Deposited:	24 Jun 2020 10:45
Last Modified:	22 May 2026 22:25
DOI:	10.1016/j.ogrm.2019.04.011
Related Websites:	Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3043644
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