Kasbekar, Anand V, Adan, Guleed H ORCID: 0000-0001-7340-4207, Beacall, Alaina, Youssef, Ahmed M, Gilkes, Catherine E and Lesser, Tristram H
(2018)
Growth Patterns of Residual Tumor in Preoperatively Growing Vestibular Schwannomas.
JOURNAL OF NEUROLOGICAL SURGERY PART B-SKULL BASE, 79 (4).
pp. 319-324.
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Abstract
<b>Objectives</b> To analyze growth of residual vestibular schwannoma (VS) following incomplete tumor resection and determine the influence of residual location and size. <b>Design</b> Retrospective case note and scan review. <b>Setting</b> Tertiary skull base unit. <b>Participants</b> Patients with residual tumor following primary surgery for medium and large unilateral growing vestibular schwanomas between 2006 and 2009. <b>Main Outcome Measures</b> Location of residual VS and post-operative growth, comparing those with more (>5%) or less than 5% of tumor residual (<5%). <b>Results</b> Fifty-two patients had visible residual tumor left behind at surgery. Twenty had < 5% and 32 had > 5% residual. The residual growth rates were 38% overall, 20% in < 5%, and 50% in > 5% residuals. There was no significant difference in growth rates at different residual locations. Median follow-up was 6.4 years. <b>Conclusions</b> There is a greater risk of regrowth of residuals > 5%. All positions of residual tumor can regrow, and the preoperative tumor size plays a role in this. Further data is needed to confirm if residual tumor in the fundus is less likely to grow.
Item Type: | Article |
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Uncontrolled Keywords: | vestibular schwannoma, residual tumor, tumor regrowth |
Depositing User: | Symplectic Admin |
Date Deposited: | 24 Feb 2020 14:43 |
Last Modified: | 19 Jan 2023 00:40 |
DOI: | 10.1055/s-0037-1607421 |
Related URLs: | |
URI: | https://livrepository.liverpool.ac.uk/id/eprint/3045282 |