Zhou, D
(2019)
Microstructure based numerical model of ocular globe.
Doctor of Philosophy thesis, University of Liverpool.
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Abstract
The human eye has been intensively explored regarding its structure and optical property as a precise optic system to receive external information. Many treatments were invented and improved to help those who suffered from visual disability or ocular diseases. Contemporary progress of experimental technique and computer methods enable scientists to understand further and even predict the biomechanical behaviour of the ocular globe. Nevertheless, it is still a challenge to accurately describe the material characteristics of ocular tissue and the realistic mechanical response. The research was conducted to develop a microstructure-based full ocular model by considering the regional variation of fibril distribution. The tissue microstructure is mainly the architecture of embedded collagen fibrils in this thesis. The microstructure findings by using X-ray indicated the potential to incorporate realistic fibril measurements that can dominate the material behaviour of ocular tissue in the numerical model. A method was developed to reconstruct X-ray maps and ensured the regularity of the fibril data covering whole eye globes. A comprehensive quantitative study was accomplished on the preference of fibril alignment ... (continues)
| Item Type: | Thesis (Doctor of Philosophy) |
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| Divisions: | Faculty of Science and Engineering > School of Engineering |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 12 Jul 2019 10:34 |
| Last Modified: | 20 Aug 2024 03:09 |
| DOI: | 10.17638/03045846 |
| Supervisors: |
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| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3045846 |
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