Saccadic Direction Errors are Associated with Impulsive Compulsive Behaviours in Parkinson's Disease Patients.



Barbosa, Pedro, Kaski, Diego, Castro, Patricia, Lees, Andrew J ORCID: 0000-0002-2476-4385, Warner, Thomas T and Djamshidian, Atbin
(2019) Saccadic Direction Errors are Associated with Impulsive Compulsive Behaviours in Parkinson's Disease Patients. Journal of Parkinson's disease.

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Abstract

Fifteen individuals with Parkinson's disease (PD) and impulsive compulsive behaviours (PD+ICB) were compared to 15 PD patients without ICBs (PD-ICB) and 15 healthy controls (HC) on a pro-saccades and an anti-saccades task to assess if ICBs are associated with distinct saccadic abnormalities. PD+ICB made shorter saccades than HC and more direction errors in the anti-saccades task than PD-ICB and HC, suggesting that patients with ICBs have greater difficulty in suppressing automatic saccades towards a given target. Saccadic assessment has the potential to evolve into a marker to guide therapeutic decisions in patients at risk of developing ICBs.

Item Type: Article
Depositing User: Symplectic Admin
Date Deposited: 05 Aug 2019 10:47
Last Modified: 19 Aug 2019 14:10
DOI: 10.3233/jpd-181460
URI: http://livrepository.liverpool.ac.uk/id/eprint/3050870
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