Ochomo, Eric, Chahilu, Mercy, Cook, Jackie, Kinyari, Teresa, Bayoh, Nabie M, West, Philippa, Kamau, Luna, Osangale, Aggrey, Ombok, Maurice, Njagi, Kiambo et al (show 8 more authors)
(2017)
Insecticide-Treated Nets and Protection against Insecticide-Resistant Malaria Vectors in Western Kenya.
EMERGING INFECTIOUS DISEASES, 23 (5).
pp. 758-764.
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Insecticide-Treated Nets and Protection against Insecticide-Resistant Malaria Vectors in Western Kenya.pdf - Published version Download (950kB) | Preview |
Abstract
Insecticide resistance might reduce the efficacy of malaria vector control. In 2013 and 2014, malaria vectors from 50 villages, of varying pyrethroid resistance, in western Kenya were assayed for resistance to deltamethrin. Long-lasting insecticide-treated nets (LLIN) were distributed to households at universal coverage. Children were recruited into 2 cohorts, cleared of malaria-causing parasites, and tested every 2 weeks for reinfection. Infection incidence rates for the 2 cohorts were 2.2 (95% CI 1.9-2.5) infections/person-year and 2.8 (95% CI 2.5-3.0) infections/person-year. LLIN users had lower infection rates than non-LLIN users in both low-resistance (rate ratio 0.61, 95% CI 0.42-0.88) and high-resistance (rate ratio 0.55, 95% CI 0.35-0.87) villages (p = 0.63). The association between insecticide resistance and infection incidence was not significant (p = 0.99). Although the incidence of infection was high among net users, LLINs provided significant protection (p = 0.01) against infection with malaria parasite regardless of vector insecticide resistance.
Item Type: | Article |
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Uncontrolled Keywords: | Animals, Humans, Malaria, Insecticides, Incidence, Cohort Studies, Follow-Up Studies, Mosquito Control, Insecticide Resistance, Child, Child, Preschool, Infant, Kenya, Female, Male, Insecticide-Treated Bednets, Public Health Surveillance, Mosquito Vectors |
Depositing User: | Symplectic Admin |
Date Deposited: | 12 Aug 2019 15:22 |
Last Modified: | 19 Jan 2023 00:31 |
DOI: | 10.3201/eid2305.161315 |
Open Access URL: | https://wwwnc.cdc.gov/eid/article/23/5/16-1315_art... |
Related URLs: | |
URI: | https://livrepository.liverpool.ac.uk/id/eprint/3051559 |