Slater, Rachael 
ORCID: 0000-0001-9765-6978
(2019)
Studies of the hindgut and faecal volatile organic compound metabolome and microbiome of the horse.
PhD thesis, University of Liverpool.
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Abstract
The horse is a hindgut fermenter which relies on microbial digestion to provide more than half of its energy requirements. Disturbances to the microbiota can lead to colic (abdominal pain), diarrhoea and other disorders in horses. Advances in techniques to characterise the equine gut microbiome have revealed that this is a complex population and many factors are thought to contribute towards the composition of species present. Epidemiological studies have identified various horse and management risk factors for colic including season (and associated management changes), foaling and tapeworm infections. The contribution of the intestinal microbiota to the development of colic in relation to these risk factors is unknown. The aim of this thesis is to investigate the association of these factors with the intestinal (or faeces as a proxy) microbiome and metabolome. Few studies to date have attempted to understand the equine gut mycobiome and functional equine microbiome (metabolome). The faecal metabolome may provide simple, cost effective markers for microbial shifts that may be associated with equine disease including increased likelihood of colic. A method to extract volatile organic compounds (VOCs) from equine ... (continues)
| Item Type: | Thesis (PhD) |
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| Divisions: | Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences > School of Medicine |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 08 Jun 2020 08:37 |
| Last Modified: | 04 Apr 2025 11:16 |
| DOI: | 10.17638/03079855 |
| Supervisors: |
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| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3079855 |
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