Limbus misrepresentation in parametric eye models

Moore, Joshua ORCID: 0000-0003-2233-2527, Shu, Xuhan, Lopes, Bernardo T, Wu, Richard and Abass, Ahmed ORCID: 0000-0002-8622-4632
(2020) Limbus misrepresentation in parametric eye models. PLOS ONE, 15 (9). e0236096-.

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<h4>Purpose</h4>To assess the axial, radial and tangential limbus position misrepresentation when parametric models are used to represent the cornea and the sclera.<h4>Methods</h4>This retrospective study included 135 subjects aged 22 to 65 years (36.5 mean ±9.8 STD), 71 females and 64 males. Topography measurements were taken using an Eye Surface Profiler topographer and processed by a custom-built MATLAB code. Eye surfaces were freed from edge-effect artefacts and fitted to spherical, conic and biconic models.<h4>Results</h4>When comparing the radial position of the limbus, average errors of -0.83±0.19mm, -0.76±0.20mm and -0.69±0.20mm were observed within the right eye population for the spherical, conic and biconic models fitted up to 5mm. For the same fitting radius, the average fitting errors were -0.86±0.23mm, -0.78±0.23mm and -0.73±0.23mm for the spherical, conic and biconic models respectively within the left eye population. For the whole cornea fit, the average errors were -0.27±0.12mm and -0.28±0.13mm for the spherical models, -0.02±0.29mm and -0.05±0.27mm for the conic models, and -0.22±0.16mm and 0.24±0.17mm for the biconic models in the right and left eye populations respectively.<h4>Conclusions</h4>Through the use of spherical, conic and biconic parametric modelling methods, the eye's limbus is being mislocated. Additionally, it is evident that the magnitude of fitting error associated with the sclera may be propagating through the other components of the eye. This suggests that a corneal nonparametric model may be necessary to improve the representation of the limbus.

Item Type: Article
Uncontrolled Keywords: Cornea, Sclera, Humans, Corneal Topography, Retrospective Studies, Algorithms, Models, Anatomic, Adult, Aged, Middle Aged, Female, Male, Young Adult
Depositing User: Symplectic Admin
Date Deposited: 02 Jul 2020 09:10
Last Modified: 18 Jan 2023 23:47
DOI: 10.1371/journal.pone.0236096
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