Case Report: Highlighting Male Genital Schistosomiasis (MGS) in Fishermen from the Southwestern Shoreline of Lake Malawi, Mangochi District

Kayuni, Sekeleghe A ORCID: 0000-0002-6948-0087, LaCourse, E James, Makaula, Peter, Lampiao, Fanuel, Juziwelo, Lazarus, Fawcett, Joanna, Shaw, Alexandra, Alharbi, Mohammad H, Verweij, Jaco J and Stothard, J Russell (2019) Case Report: Highlighting Male Genital Schistosomiasis (MGS) in Fishermen from the Southwestern Shoreline of Lake Malawi, Mangochi District. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 101 (6). pp. 1331-1335.

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Official URL: http://dx.doi.org/10.4269/ajtmh.19-0562

Abstract

Urogenital schistosomiasis causes morbidity within the genitalia but is underreported and infrequently examined in men. To draw attention to male genital schistosomiasis (MGS), a longitudinal cohort study was conducted among fishermen along the southwestern shoreline of Lake Malawi. A case series of five participants is presented inclusive of questionnaire interviews, parasitological examinations, ultrasonography, and provision of a standard dose (40 mg/kg) of praziquantel (PZQ) treatment at baseline, 1-, 3-, 6-, and 12-month follow-up time points. Eggs of <i>Schistosoma haematobium</i> were observed in urine or semen across all time points; parasitological diagnostics were bolstered by real-time PCR for <i>Schistosoma</i> DNA in semen and by portable ultrasonography to document putative MGS-associated morbidity. We highlight the importance of developing standard diagnostic tests for MGS and increasing the accessibility of PZQ treatment to men, especially those in at-risk endemic areas.

Item Type:	Article
Uncontrolled Keywords:	Genitalia, Male, Semen, Animals, Humans, Schistosoma haematobium, Schistosomiasis haematobia, Praziquantel, Anthelmintics, Ultrasonography, Parasite Egg Count, Longitudinal Studies, Fisheries, Adult, Middle Aged, Malawi, Male, Young Adult, Lakes, Surveys and Questionnaires
Depositing User:	Symplectic Admin
Date Deposited:	06 Jul 2020 08:52
Last Modified:	18 Jan 2023 23:46
DOI:	10.4269/ajtmh.19-0562
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3092903