The role of Ca2+ signalling in the physiology and pathophysiology of exocrine pancreas

Chvanov, Michael, Voronina, Svetlana, Criddle, David N ORCID: 0000-0003-2952-8450 and Tepikin, Alexei V (2020) The role of Ca2+ signalling in the physiology and pathophysiology of exocrine pancreas Current Opinion in Physiology, 17. pp. 96-105. ISSN 2468-8673, 2468-8673

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Abstract

The purpose of this paper is to describe recent advances in the studies of Ca2+ signalling and its physiological/pathophysiological roles in the cells of exocrine pancreas. The review is primarily focused on pancreatic acinar cells — this reflects the importance of this cell type for unravelling of Ca2+ signalling mechanisms and downstream functions. Valuable information on the functional relevance of Ca2+ signalling was also recently obtained in studies of pancreatic ductal cells and pancreatic stellate cells; progress in the studies of these cell types is also briefly summarised in this paper.

Item Type:	Article
Uncontrolled Keywords:	3208 Medical Physiology, 32 Biomedical and Clinical Sciences, Pancreatic Cancer, Rare Diseases, Cancer, Digestive Diseases, 2.1 Biological and endogenous factors
Depositing User:	Symplectic Admin
Date Deposited:	09 Sep 2020 08:06
Last Modified:	02 Jul 2026 20:00
DOI:	10.1016/j.cophys.2020.07.013
Related Websites:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3100502
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