Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity



Volz, Erik ORCID: 0000-0001-6268-8937, Hill, Verity ORCID: 0000-0002-3509-8146, McCrone, John T ORCID: 0000-0002-9846-8917, Price, Anna ORCID: 0000-0002-0769-0417, Jorgensen, David ORCID: 0000-0003-4982-3764, O’Toole, Áine, Southgate, Joel ORCID: 0000-0003-3042-7761, Johnson, Robert ORCID: 0000-0002-7365-0042, Jackson, Ben, Nascimento, Fabricia F
et al (show 571 more authors) (2021) Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity. Cell, 184 (1). 64-75.e11.

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Abstract

Analysis of the spread and frequency of SARS-CoV-2 D614G in the United Kingdom suggests a selective advantage for this strain that is associated with higher viral loads in younger patients but not higher COVID-19 clinical severity or mortality.

Item Type: Article
Depositing User: Symplectic Admin
Date Deposited: 25 Nov 2020 11:20
Last Modified: 18 Jan 2023 23:20
DOI: 10.1016/j.cell.2020.11.020
Open Access URL: https://doi.org/10.1016/j.cell.2020.11.020
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3108002