Salmonella identified in pigs in Kenya and Malawi reveals the potential for zoonotic transmission in emerging pork markets


Wilson, Catherine N, Pulford, Caisey V, Akoko, James, Perez Sepulveda, Blanca ORCID: 0000-0002-2891-4010, Predeus, Alex V, Bevington, Jessica, Duncan, Patricia, Hall, Neil, Wigley, Paul, Feasey, Nicholas et al (show 4 more authors) (2020) Salmonella identified in pigs in Kenya and Malawi reveals the potential for zoonotic transmission in emerging pork markets PLOS NEGLECTED TROPICAL DISEASES, 14 (11). pp. 1-16. ISSN 1935-2735, 1935-2735

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Abstract

Salmonella is a major cause of foodborne disease globally. Pigs can carry and shed non-typhoidal Salmonella (NTS) asymptomatically, representing a significant reservoir for these pathogens. To investigate Salmonella carriage by African domestic pigs, faecal and mesen-teric lymph node samples were taken at slaughter in Nairobi, Busia (Kenya) and Chikwawa (Malawi) between October 2016 and May 2017. Selective culture, antisera testing and whole genome sequencing were performed on samples from 647 pigs; the prevalence of NTS carriage was 12.7% in Busia, 9.1% in Nairobi and 24.6% in Chikwawa. Two isolates of S. Typhimurium ST313 were isolated, but were more closely related to ST313 isolates associated with gastroenteritis in the UK than bloodstream infection in Africa. The discovery of porcine NTS carriage in Kenya and Malawi reveals potential for zoonotic transmission of diarrhoeal strains to humans in these countries, but not for transmission of clades specifi-cally associated with invasive NTS disease in Africa.

Item Type: Article
Uncontrolled Keywords: Lymph Nodes, Animals, Swine, Humans, Salmonella typhimurium, Salmonella Infections, Animal, Gastroenteritis, Microbial Sensitivity Tests, Drug Resistance, Multiple, Bacterial, Kenya, Malawi, Foodborne Diseases, Molecular Typing, Whole Genome Sequencing, Pork Meat, Bacterial Zoonoses
Depositing User: Symplectic Admin
Date Deposited: 04 Dec 2020 10:11
Last Modified: 16 Jun 2026 15:14
DOI: 10.1371/journal.pntd.0008796
Open Access URL: https://doi.org/10.1371/journal.pntd.0008796
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URI: https://livrepository.liverpool.ac.uk/id/eprint/3109171
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