Amplicon based MinION sequencing of SARS-CoV-2 and metagenomic characterisation of nasopharyngeal swabs from patients with COVID-19



Moore, Shona ORCID: 0000-0001-8610-2806, Penrice-Randal, Rebekah, Alruwaili, Muhannad, Dong, Xiaofeng, Pullan, Steven, Carter, Daniel, Bewley, Kevin ORCID: 0000-0002-9078-6734, Zhao, Qin, Sun, Yani, Hartley, Catherine
et al (show 20 more authors) (2020) Amplicon based MinION sequencing of SARS-CoV-2 and metagenomic characterisation of nasopharyngeal swabs from patients with COVID-19.

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Abstract

COVID-19 is a complex disease phenotype where the underlying microbiome could influence morbidity and mortality. Amplicon and metagenomic MinION based sequencing was used to rapidly (within 8 hours) identify SARS-CoV-2 and assess the microbiome in nasopharyngeal swabs obtained from patients with COVID-19 by the ISARIC 4C consortium.

Item Type: Article
Depositing User: Symplectic Admin
Date Deposited: 08 Jan 2021 15:16
Last Modified: 22 Sep 2021 11:22
DOI: 10.1101/2020.03.05.20032011
Open Access URL: https://doi.org/10.1101/2020.03.05.20032011
URI: https://livrepository.liverpool.ac.uk/id/eprint/3112074