Percutaneous cervical cordotomy for cancer-related pain: prospective multimodal outcomes evaluation

Doyle, Aimee, Sharma, Manohar Lal, Gupta, Manish, Goebel, Andreas ORCID: 0000-0002-3763-8206 and Marley, Kate (2022) Percutaneous cervical cordotomy for cancer-related pain: prospective multimodal outcomes evaluation. BMJ SUPPORTIVE & PALLIATIVE CARE, 12 (E1). E21-E27.

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Abstract

<h4>Background</h4>Percutaneous cervical cordotomy (PCC) offers pain relief to patients with unilateral treatment-refractory cancer-related pain. There is insufficient evidence about any effects of this intervention on patients' quality of life.<h4>Method</h4>Comprehensive multimodal assessment to determine how PCC affects pain, analgesic intake and quality of life of patients with medically refractory, unilateral cancer-related pain.This study was set in a multidisciplinary, tertiary cancer pain service. Patient outcomes immediately following PCC were prospectively recorded. Patients were also followed up at 4 weeks.<h4>Results</h4>Outcome variables collected included: background and breakthrough pain numerical rating scores before PCC, at discharge and 4 weeks postprocedure; oral morphine equivalent opioid dose changes, Patient's Global Impression of Change, Eastern Cooperative oncology group performance status and health related quality of life score, that is, EuroQol-5 dimension-5 level (EQ-5D).<h4>Conclusions</h4>Despite significant improvement in pain and other standard outcomes sustained at 4 weeks, there was little evidence of improvement in EQ-5D scores. In patients with terminal cancer, improved pain levels following cordotomy for cancer-related pain does not appear to translate into improvements in overall quality of life as assessed with the generic EQ-5D measure.

Item Type:	Article
Uncontrolled Keywords:	cancer, pain
Depositing User:	Symplectic Admin
Date Deposited:	11 Jan 2021 11:23
Last Modified:	18 Jan 2023 23:05
DOI:	10.1136/bmjspcare-2019-002084
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3112264