Staphylococcus aureus Keratitis: Incidence, Pathophysiology, Risk Factors and Novel Strategies for Treatment



Lee, Jason W, Somerville, Tobi, Kaye, Stephen B ORCID: 0000-0003-0390-0592 and Romano, Vito ORCID: 0000-0002-5148-7643
(2021) Staphylococcus aureus Keratitis: Incidence, Pathophysiology, Risk Factors and Novel Strategies for Treatment. Journal of Clinical Medicine, 10 (4). p. 758.

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Abstract

<jats:p>Bacterial keratitis is a devastating condition that can rapidly progress to serious complications if not treated promptly. Certain causative microorganisms such as Staphylococcus aureus and Pseudomonas aeruginosa are notorious for their resistance to antibiotics. Resistant bacterial keratitis results in poorer outcomes such as scarring and the need for surgical intervention. Thorough understanding of the causative pathogen and its virulence factors is vital for the discovery of novel treatments to avoid further antibiotic resistance. While much has been previously reported on P. aeruginosa, S. aureus has been less extensively studied. This review aims to give a brief overview of S. aureus epidemiology, pathophysiology and clinical characteristics as well as summarise the current evidence for potential novel therapies.</jats:p>

Item Type: Article
Uncontrolled Keywords: keratitis, microbial keratitis, Staphylococcus aureus, pathophysiology, novel therapy, therapeutics, treatment
Depositing User: Symplectic Admin
Date Deposited: 03 Mar 2021 11:56
Last Modified: 18 Jan 2023 22:57
DOI: 10.3390/jcm10040758
Open Access URL: https://doi.org/10.3390/jcm10040758
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3116454