Enantioselective Intermolecular Murai-Type Alkene Hydroarylation Reactions



Aldhous, Timothy P ORCID: 0000-0003-2031-7454, Chung, Raymond WM, Dalling, Andrew G and Bower, John F ORCID: 0000-0002-7551-8221
(2021) Enantioselective Intermolecular Murai-Type Alkene Hydroarylation Reactions. SYNTHESIS-STUTTGART, 53 (17). pp. 2961-2975.

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Abstract

<jats:title>Abstract</jats:title><jats:p>Strategies that enable the efficient assembly of complex building blocks from feedstock chemicals are of paramount importance to synthetic chemistry. Building upon the pioneering work of Murai and co-workers in 1993, C–H-activation-based enantioselective hydroarylations of alkenes offer a particularly promising framework for the step- and atom-economical installation of benzylic stereocenters. This short review presents recent intermolecular enantioselective Murai-type alkene hydroarylation methodologies and the mechanisms by which they proceed.</jats:p><jats:p>1 Introduction</jats:p><jats:p>2 Enantioselective Hydroarylation Reactions of Strained Bicyclic Alkenes</jats:p><jats:p>3 Enantioselective Hydroarylation Reactions of Electron-Rich Acyclic Alkenes</jats:p><jats:p>4 Enantioselective Hydroarylation Reactions of Electron-Poor Acyclic Alkenes</jats:p><jats:p>5 Enantioselective Hydroarylation Reactions of Minimally Polarized Acyclic Alkenes</jats:p><jats:p>6 Conclusion and Outlook</jats:p>

Item Type: Article
Uncontrolled Keywords: enantioselective, hydroarylation, C-H activation, catalysis, transition metal
Divisions: Faculty of Science and Engineering > School of Physical Sciences
Depositing User: Symplectic Admin
Date Deposited: 20 Apr 2021 10:49
Last Modified: 18 Jan 2023 22:51
DOI: 10.1055/s-0040-1720406
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3119917