Imaging of vascular abnormalities in ocular surface disease



Romano, Vito ORCID: 0000-0002-5148-7643, Steger, Bernhard, Ahmad, Mohammad ORCID: 0000-0002-5972-0358, Coco, Giulia, Pagano, Luca, Ahmad, Sajjad, Zhao, Yitian, Zheng, Yalin ORCID: 0000-0002-7873-0922 and Kaye, Stephen B ORCID: 0000-0003-0390-0592
(2022) Imaging of vascular abnormalities in ocular surface disease. SURVEY OF OPHTHALMOLOGY, 67 (1). pp. 31-51.

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Abstract

The vascular system of the ocular surface plays a central role in infectious, autoimmune, inflammatory, traumatic and neoplastic diseases. The development, application, and monitoring of treatments for vascular abnormalities depends on the in vivo analysis of the ocular surface vasculature. Until recently, ocular surface vascular imaging was confined to biomicroscopic and color photographic assessment, both limited by poor reproducibility and the inability to image lymphatic vasculature in vivo. The evolvement and clinical implementation of innovative imaging modalities including confocal microscopy, intravenous, and optical coherence tomography-based angiography now allows standardized quantitative and functional vascular assessment with potential applicability to automated analysis algorithms and diagnostics.

Item Type: Article
Uncontrolled Keywords: Ocular surface, Vascularization, Corneal neovascularization, OCT-A, angiography, Fine needle
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences
Depositing User: Symplectic Admin
Date Deposited: 10 May 2021 10:01
Last Modified: 18 Jan 2023 22:49
DOI: 10.1016/j.survophthal.2021.05.001
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3121745