Critical deterioration in children admitted to hospital, requiring emergency transfer to the Paediatric Intensive Care Unit

Sefton, Geraldine (2021) Critical deterioration in children admitted to hospital, requiring emergency transfer to the Paediatric Intensive Care Unit PhD thesis, University of Liverpool.

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Abstract

Introduction. Critical deterioration in children admitted to hospital, which results in emergency transfer to the Paediatric Intensive Care Unit (PICU), is associated with increased morbidity and mortality. To date, the interventions aimed at reducing critical deterioration have focused on Paediatric Early Warning Scores (PEWS) and/or Rapid Response Team (RRT) utilisation. This thesis explored the association between antecedent risk factors and Critical Deterioration Events (CDE), and the clinical impact of PEWS utilisation on CDE and outcome. Finally, the proof-of-concept testing for an Electronic Physiological Surveillance System (EPSS) is presented, as an aid to deterioration recognition in children admitted to hospital. Methods. A fourteen-year dataset of PICU admissions, collected prospectively, was used to conduct a post-hoc epidemiological study. Antecedent risk factors associated with CDE were identified by comparing characteristics of the CDE cohort with other PICU admissions. The impact of PEWS, in different formats, on CDE were evaluated by comparing time segments of traditional clinical care (baseline) with the use of a paper-based PEWS trigger tool, a paper-based age-specific aggregate PEWS score ... (continues)

Item Type:	Thesis (PhD)
Uncontrolled Keywords:	Paediatric Early Warning, Pediatric Early Warning, PEWS
Divisions:	Faculty of Health & Life Sciences
Depositing User:	Symplectic Admin
Date Deposited:	09 Sep 2021 13:16
Last Modified:	08 Feb 2025 02:18
DOI:	10.17638/03125494
Supervisors:	Carrol, Enitan ORCID: 0000-0001-8357-7726 Lane, Steven
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3125494
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