Case Report: Toxigenic Corynebacterium ulcerans Diphtheria-Like Infection in a Horse in the United Kingdom

Zendri, Flavia ORCID: 0000-0002-7776-9278, Isgren, Cajsa Marie, Sinovich, Matthew, Richards-Rios, Peter, Hopkins, Katie L, Russell, Katherine, Groves, Natalie, Litt, David, Fry, Norman K and Timofte, Dorina ORCID: 0000-0002-7261-738X (2021) Case Report: Toxigenic Corynebacterium ulcerans Diphtheria-Like Infection in a Horse in the United Kingdom FRONTIERS IN VETERINARY SCIENCE, 8. 650238-. ISSN 2297-1769, 2297-1769

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Abstract

Corynebacterium ulcerans (C. ulcerans) may cause diphtheria in humans and can be carried by a wide range of animal species including dairy cows and, more recently, dogs and cats that have been increasingly involved in zoonotic trasmission. We isolated and characterized, by WGS, a toxigenic C. ulcerans strain from a diseased horse in the United Kingdom showing clinical signs of respiratory diphtheria comparable to those seen in people. Our results indicate a role for horses as reservoirs for zoonotic C. ulcerans.

Item Type:	Article
Uncontrolled Keywords:	emerging zoonosis, toxigenic Corynebacterium ulcerans, horse, respiratory diphtheria-like illness, WGS, ST543
Divisions:	Faculty of Health & Life Sciences Faculty of Health & Life Sciences > Inst. Infection, Vet & Ecological Sciences
Depositing User:	Symplectic Admin
Date Deposited:	11 Jun 2021 15:16
Last Modified:	16 Jun 2026 10:36
DOI:	10.3389/fvets.2021.650238
Open Access URL:	https://doi.org/10.3389/fvets.2021.650238
Related Websites:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3126002
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