Smith, Shirley L, Afonso, Maria M, Roberts, Larry, Noble, Peter‐John M ORCID: 0000-0002-2275-2014, Pinchbeck, Gina L
ORCID: 0000-0002-5671-8623 and Radford, Alan D
ORCID: 0000-0002-4590-1334
(2021)
A virtual biobank for companion animals: A parvovirus pilot study.
Veterinary Record, 189 (6).
244-+.
ISSN 0042-4900, 2042-7670
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Abstract
<h4>Background</h4>There is a lack of national population data concerning infectious disease in companion animals. Here, we piloted the feasibility of linking diagnostic laboratories, population surveillance and modern sequencing approaches to extract targeted diagnostic samples from laboratories before they were discarded, as a novel route to better understand national epidemiology of major small animal pathogens.<h4>Methods</h4>Samples tested for canine or feline parvovirus were requested from a national veterinary diagnostic laboratory and analysed by Sanger or next generation sequencing. Samples were linked to electronic health data held in the SAVSNET database.<h4>Results</h4>Sequences obtained from positive samples, together with associated metadata, provided new insights into the recent geographical distribution of parvovirus strains in circulation in the United Kingdom (UK).<h4>Conclusions</h4>This collaboration with industry represents a 'National Virtual Biobank' that can rapidly be called on, to efficiently add new layers of epidemiological information of relevance to animal, and potentially human, population health.
Item Type: | Article |
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Uncontrolled Keywords: | Animals, Dogs, Cats, Parvovirus, Feline panleukopenia virus, Parvovirus, Canine, Parvoviridae Infections, Cat Diseases, Dog Diseases, Pilot Projects, Biological Specimen Banks |
Divisions: | Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Infection, Veterinary and Ecological Sciences |
Depositing User: | Symplectic Admin |
Date Deposited: | 15 Jun 2021 08:43 |
Last Modified: | 06 Dec 2024 21:14 |
DOI: | 10.1002/vetr.556 |
Related URLs: | |
URI: | https://livrepository.liverpool.ac.uk/id/eprint/3126282 |