A virtual biobank for companion animals: A parvovirus pilot study

Smith, Shirley L, Afonso, Maria M, Roberts, Larry, Noble, Peter‐John M, Pinchbeck, Gina L ORCID: 0000-0002-5671-8623 and Radford, Alan D ORCID: 0000-0002-4590-1334
(2021) A virtual biobank for companion animals: A parvovirus pilot study. Veterinary Record, 189 (6). 244-+.

[img] Slideshow
Parvovirus final image 2ar.pptx - Author Accepted Manuscript

Download (111kB)
[img] Text
Smith et al resubmission March 2021 accepted.docx - Author Accepted Manuscript

Download (65kB)


<h4>Background</h4>There is a lack of national population data concerning infectious disease in companion animals. Here, we piloted the feasibility of linking diagnostic laboratories, population surveillance and modern sequencing approaches to extract targeted diagnostic samples from laboratories before they were discarded, as a novel route to better understand national epidemiology of major small animal pathogens.<h4>Methods</h4>Samples tested for canine or feline parvovirus were requested from a national veterinary diagnostic laboratory and analysed by Sanger or next generation sequencing. Samples were linked to electronic health data held in the SAVSNET database.<h4>Results</h4>Sequences obtained from positive samples, together with associated metadata, provided new insights into the recent geographical distribution of parvovirus strains in circulation in the United Kingdom (UK).<h4>Conclusions</h4>This collaboration with industry represents a 'National Virtual Biobank' that can rapidly be called on, to efficiently add new layers of epidemiological information of relevance to animal, and potentially human, population health.

Item Type: Article
Uncontrolled Keywords: Animals, Dogs, Cats, Parvovirus, Feline panleukopenia virus, Parvovirus, Canine, Parvoviridae Infections, Cat Diseases, Dog Diseases, Pilot Projects, Biological Specimen Banks
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Infection, Veterinary and Ecological Sciences
Depositing User: Symplectic Admin
Date Deposited: 15 Jun 2021 08:43
Last Modified: 18 Jan 2023 22:35
DOI: 10.1002/vetr.556
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3126282