Thakur, Kiran T, Tamborska, Arina ORCID: 0000-0003-4661-8407, Wood, Greta K ORCID: 0000-0001-6098-2331, McNeill, Emily, Roh, David, Akpan, Imo J, Miller, Eliza C, Bautista, Alyssa, Claassen, Jan, Kim, Carla Y et al (show 11 more authors)
(2021)
Clinical review of cerebral venous thrombosis in the context of COVID-19 vaccinations: Evaluation, management, and scientific questions.
Journal of the Neurological Sciences, 427.
p. 117532.
Text
PIIS0022510X21002264.pdf - Published version Download (1MB) | Preview |
Abstract
<h4>Background</h4>Vaccine induced immune mediated thrombocytopenia or VITT, is a recent and rare phenomenon of thrombosis with thrombocytopenia, frequently including cerebral venous thromboses (CVT), that has been described following vaccination with adenovirus vaccines ChAdOx1 nCOV-19 (AstraZeneca) and Ad26.COV2·S Johnson and Johnson (Janssen/J&J). The evaluation and management of suspected cases of CVT post COVID-19 vaccination are critical skills for a broad range of healthcare providers.<h4>Methods</h4>A collaborative comprehensive review of literature was conducted among a global group of expert neurologists and hematologists.<h4>Findings</h4>Strategies for rapid evaluation and treatment of the CVT in the context of possible VITT exist, including inflammatory marker measurements, PF4 assays, and non-heparin anticoagulation.
Item Type: | Article |
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Uncontrolled Keywords: | Cerebral venous thrombosis, COVID-19, Vaccination |
Divisions: | Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Infection, Veterinary and Ecological Sciences |
Depositing User: | Symplectic Admin |
Date Deposited: | 15 Jun 2021 07:56 |
Last Modified: | 18 Jan 2023 22:34 |
DOI: | 10.1016/j.jns.2021.117532 |
Related URLs: | |
URI: | https://livrepository.liverpool.ac.uk/id/eprint/3126308 |