Plasma Rich in Growth Factors (PRGF) in Transepithelial Photorefractive Keratectomy (TPRK)



Sanchez-Gonzalez, Jose-Maria, Alonso-Aliste, Federico, Borroni, Davide ORCID: 0000-0001-6952-5647, Amian-Cordero, Jonatan, De-Hita-Cantalejo, Concepcion, Capote-Puente, Raul, Bautista-Llamas, Maria-Jose, Sanchez-Gonzalez, Maria Carmen, Rodriguez-Calvo-de-Mora, Marina and Rocha-de-Lossada, Carlos
(2021) Plasma Rich in Growth Factors (PRGF) in Transepithelial Photorefractive Keratectomy (TPRK). JOURNAL OF CLINICAL MEDICINE, 10 (9). 1939-.

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Abstract

To evaluate the usage of plasma rich in growth factor (PRGF) in transepithelial photorefractive keratectomy (TPRK) in low and moderate myopia, patients who underwent myopic and astigmatism TPRK with PRGF were involved in this retrospective, observational study. Subjects underwent a surgical procedure between February 2019 and June 2019. A three-month follow-up was recorded. Pain score was assessed with a visual analogue scale (0-10) and re-epithelialization time recorded. A total of 48 eyes from 24 patients were recruited. Mean uncorrected distance visual acuity (UDVA) was 20/20.31 (0.00 ± 0.02 LogMAR). A total of 98% of eyes did not change corrected distance visual acuity (CDVA) lines. Two percent of eyes lost one line of CDVA. Preoperative spherical equivalent was -2.67 ± 1.37 D and after three months changed to -0.21 ± 0.34 D, and 2% of eyes changed 0.50 D or more between one and three months. Pain score was 3.29 ± 0.61 (3 to 6) score points at day one and 0.08 ± 0.27 score points at day seven. Finally, re-epithelialization time was 2.50 ± 1.20 days. PRGF addition to conventional refractive treatment such as TPRK seems to alleviate immediate postoperative pain and positively contribute to corneal re-epithelization time.

Item Type: Article
Uncontrolled Keywords: plasma rich in growth factor, photorefractive keratectomy, transepithelial photorefractive keratectomy, visual outcomes, refractive outcomes
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences
Depositing User: Symplectic Admin
Date Deposited: 30 Jun 2021 12:38
Last Modified: 18 Jan 2023 21:37
DOI: 10.3390/jcm10091939
Open Access URL: https://www.mdpi.com/2077-0383/10/9/1939
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3128264