Karyotaki, Eirini, Sijbrandij, Marit, Purgato, Marianna, Acarturk, Ceren, Lakin, Daniel, Bailey, Della, Peckham, Emily, Uygun, Ersin, Tedeschi, Federico, Wancata, Johannes et al (show 17 more authors)
(2021)
Self-help plus for refugees and asylum seekers; study protocol for a series of individual participant data meta-analyses.
EUROPEAN JOURNAL OF PSYCHOTRAUMATOLOGY, 12 (1).
1930690-.
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Abstract
<h4>Background</h4>Refugees and asylum seekers face various stressors due to displacement and are especially vulnerable to common mental disorders. To effectively manage psychological distress in this population, innovative interventions are required. The World Health Organization (WHO) Self-Help Plus (SH+) intervention has shown promising outcomes in reducing symptoms of common mental disorders among refugees and asylum seekers. However, individual participant differences in response to SH+ remain largely unknown. The Individual Participant Data (IPD) meta-analysis synthesizes raw datasets of trials to provide cutting-edge evidence of outcomes that cannot be examined by conventional meta-analytic approaches.<h4>Objectives</h4>This protocol outlines the methods of a series of IPD meta-analyses aimed at examining the effects and potential moderators of SH+ in (a) reducing depressive symptoms at post-intervention and (b) preventing the six-month cumulative incidence of mental disorders in refugees and asylum seekers.<h4>Method</h4>RCTs on SH+ have been identified through WHO and all authors have agreed to share the datasets of the trials. The primary outcomes of the IPD meta-analyses are (a) reduction in depressive symptoms at post-intervention, and (b) prevention of six-month cumulative incidence of mental disorders. Secondary outcomes include post-traumatic stress disorder symptoms, well-being, functioning, quality of life, and twelve-month cumulative incidence of mental disorders. One-stage IPD meta-analyses will be performed using mixed-effects linear/logistic regression. Missing data will be handled by multiple imputation.<h4>Conclusions</h4>These results will enrich current knowledge about the response to SH+ and will facilitate its targeted dissemination. The results of these IPD meta-analyses will be published in peer-reviewed journals.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Refugees, asylum seekers, individual participant data, depression, common mental disorders |
| Divisions: | Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Population Health |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 17 Dec 2021 09:46 |
| Last Modified: | 18 Jan 2023 21:35 |
| DOI: | 10.1080/20008198.2021.1930690 |
| Open Access URL: | https://doi.org/10.1080/20008198.2021.1930690 |
| Related URLs: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3130826 |
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