Communicating assemblies of biomimetic nanocapsules

Zhou, Hongda, Huang, Haowei, Bahri, Mounib ORCID: 0000-0002-8336-9158, Browning, Nigel D ORCID: 0000-0003-0491-251X, Smith, James, Graham, Michael and Shchukin, Dmitry ORCID: 0000-0002-2936-804X
(2021) Communicating assemblies of biomimetic nanocapsules. NANOSCALE, 13 (26). pp. 11343-11348.

Access the full-text of this item by clicking on the Open Access link.


Communication assemblies between biomimetic nanocapsules in a 3D closed system with self-regulating and self-organization functionalities were demonstrated for the first time. Two types of biomimetic nanocapsules, TiO2/polydopamine capsules and SiO2/polyelectrolytes capsules with different stimuli-responsive properties were prepared and leveraged to sense the external stimulus, transmit chemical signaling, and autonomic communication-controlled release of active cargos. The capsules have clear core-shell structures with average diameters of 30 nm and 25 nm, respectively. The nitrogen adsorption-desorption isotherms and thermogravimetric analysis displayed their massive pore structures and encapsulation capacity of 32% of glycine pH buffer and 68% of benzotriazole, respectively. Different from the direct release mode of the single capsule, the communication assemblies show an autonomic three-stage release process with a "jet lag" feature, showing the internal modulation ability of self-controlled release efficiency. The control overweight ratios of capsules influences on communication-release interaction between capsules. The highest communication-release efficiency (89.6% of benzotriazole) was achieved when the weight ratio of TiO2/polydopamine/SiO2/polyelectrolytes capsules was 5 : 1 or 10 : 1. Communication assemblies containing various types of nanocapsules can autonomically perform complex tasks in a biomimetic fashion, such as cascaded amplification and multidirectional communication platforms in bioreactors.

Item Type: Article
Uncontrolled Keywords: Silicon Dioxide, Biomimetics, Adsorption, Nanocapsules, Polyelectrolytes
Divisions: Faculty of Science and Engineering > School of Engineering
Faculty of Science and Engineering > School of Physical Sciences
Depositing User: Symplectic Admin
Date Deposited: 23 Jul 2021 07:11
Last Modified: 18 Jan 2023 21:35
DOI: 10.1039/d1nr03170h
Open Access URL:
Related URLs: