Zhang, Juqian 
ORCID: 0000-0002-9653-8635, Bisson, Arnaud, Boumhidi, Jad, Herbert, Julien, Saint Etienne, Christophe, Bernard, Anne, Lip, Gregory YH ORCID: 0000-0002-7566-1626 and Fauchier, Laurent
(2021)
The Prognosis of Baseline Mitral Regurgitation in Patients with Transcatheter Aortic Valve Implantation.
JOURNAL OF CLINICAL MEDICINE, 10 (17).
3974-.
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The Prognosis of Baseline Mitral Regurgitation in Patients with Transcatheter Aortic Valve Implantation.pdf - Published version Download (1MB) | Preview |
Abstract
Mitral regurgitation (MR) is the most common valvular lesion in transcatheter aortic valve implantation (TAVI) recipients. This study aims to assess the long-term prognostic impact of baseline MR in TAVI patients. Adult patients who underwent TAVI were identified in the French National Hospital Discharge Database. All-cause and cardiovascular mortality, stroke, and rehospitalization with heart failure (HF) were compared in TAVI patients with and without baseline MR and tricuspid regurgitation (TR), respectively; the associations of MR and TR with the outcomes were assessed by Cox regression. Baseline MR was identified in 8240 TAVI patients. Patients with baseline MR have higher yearly incidence of all-cause mortality (HR: 1.192, 95% confidence interval CI: 1.125-1.263), cardiovascular mortality (HR: 1.313, 95%CI: 1.210-1.425), and rehospitalization for heart failure (HF) (HR: 1.411, 95%CI: 1.340-1.486) compared to those without, except for stroke rate (HR: 0.988, 95%CI: 0.868-1.124). Neither baseline MR nor TR was an independent risk predictor for all-cause mortality or cardiovascular mortality in TAVI patients. Baseline MR was independently associated with rehospitalization for HF in TAVI patients. Baseline MR and TR were associated with increased all-cause and cardiovascular mortality post-TAVI, however, neither of them was independent predictor for all-cause or cardiovascular mortality.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | transcatheter aortic valve implantation, mitral regurgitation, tricuspid regurgitation, all-cause mortality, cardiovascular mortality |
| Divisions: | Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 21 Dec 2021 16:16 |
| Last Modified: | 18 Jan 2023 21:18 |
| DOI: | 10.3390/jcm10173974 |
| Related URLs: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3145819 |
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