4S-AF scheme and ABC pathway guided management improves outcomes in atrial fibrillation patients.



Guo, Yutao, Imberti, Jacopo F, Kotalczyk, Agnieszka, Wang, Yutang, Lip, Gregory YH ORCID: 0000-0002-7566-1626 and ChiOTEAF Registry Investigators
(2022) 4S-AF scheme and ABC pathway guided management improves outcomes in atrial fibrillation patients. European journal of clinical investigation, 52 (6). e13751-e13751.

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Abstract

<h4>Background</h4>The 4S-AF scheme and the ABC pathway for integrated care have been proposed to better characterize and treat patients with atrial fibrillation (AF). We aimed to evaluate the assessment of the 4S-AF scheme and ABC pathway in Chinese AF patients.<h4>Methods</h4>The ChiOTEAF is a prospective, observational, multicentre registry. Consecutive AF patients from 44 centres across 20 Chinese provinces with available 1-year follow-up data were included.<h4>Results</h4>A total of 6419 patients were included, median age 76 years (interquartile range 67-83; 39.1% female). Of these, 3503 (59.8%) patients were not characterized using the 4S-AF scheme and not management according to the ABC pathway (group 1); 1795 (28.0%) were characterized according to the 4S-AF scheme but ABC pathway non-adherent or vice versa (group 2); and 1121 (17.4%) characterized according to the 4S-AF scheme and were ABC pathway adherent (group 3). As compared with group 1, group 2 and group 3 were independently associated with lower odds of the composite endpoint of all-cause death/any thromboembolic event, with the greatest benefit observed in group 3 (OR: 0.19; 95% CI 0.12-0.31) [for group 2: OR: 0.28; 95% CI 0.20-0.37]. Similar results were observed for all-cause death (group 2: OR: 0.18; 95% CI 0.12-0.27; group 3: OR: 0.14; 95% CI 0.07-0.25).<h4>Conclusions</h4>In a contemporary real-word cohort of Chinese AF patients, it is feasible to characterize and manage AF patients using the novel 4S-AF scheme and ABC pathway for integrated care. The use of both these tools is associated with improved clinical outcomes.

Item Type: Article
Uncontrolled Keywords: ChiOTEAF Registry Investigators
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences
Depositing User: Symplectic Admin
Date Deposited: 03 Mar 2022 10:16
Last Modified: 18 Jan 2023 21:11
DOI: 10.1111/eci.13751
Open Access URL: https://doi.org/10.1111/eci.13751
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3150023