Supramolecular Engineering of Alkylated, Fluorinated, and Mixed Amphiphiles.



Rashmi, Rashmi, Hasheminejad, Hooman ORCID: 0000-0002-9939-5326, Herziger, Svenja ORCID: 0000-0003-4147-7916, Mirzaalipour, Alireza, Singh, Abhishek K, Netz, Roland R ORCID: 0000-0003-0147-0162, Böttcher, Christoph, Makki, Hesam, Sharma, Sunil K and Haag, Rainer ORCID: 0000-0003-3840-162X
(2022) Supramolecular Engineering of Alkylated, Fluorinated, and Mixed Amphiphiles. Macromolecular rapid communications, 43 (8). e2100914 - ?.

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Abstract

The rational design of perfluorinated amphiphiles to control the supramolecular aggregation in an aqueous medium is still a key challenge for the engineering of supramolecular architectures. Here, the synthesis and physical properties of six novel non-ionic amphiphiles are presented. The effect of mixed alkylated and perfluorinated segments in a single amphiphile is also studied and compared with only alkylated and perfluorinated units. To explore their morphological behavior in an aqueous medium, dynamic light scattering (DLS) and cryogenic transmission electron microscopy/electron microscopy (cryo-TEM/EM) measurements are used. The assembly mechanisms with theoretical investigations are further confirmed, using the Martini model to perform large-scale coarse-grained molecular dynamics simulations. These novel synthesized amphiphiles offer a greater and more systematic understanding of how perfluorinated systems assemble in an aqueous medium and suggest new directions for rational designing of new amphiphilic systems and interpreting their assembly process.

Item Type: Article
Uncontrolled Keywords: Microscopy, Electron, Transmission, Molecular Dynamics Simulation
Divisions: Faculty of Science and Engineering > School of Physical Sciences
Depositing User: Symplectic Admin
Date Deposited: 11 May 2022 11:19
Last Modified: 05 Oct 2022 20:07
DOI: 10.1002/marc.202100914
Open Access URL: https://onlinelibrary.wiley.com/doi/10.1002/marc.2...
URI: https://livrepository.liverpool.ac.uk/id/eprint/3154604