Current Perspectives on Corneal Transplantation.

Liu, Siyin, Wong, Yee Ling ORCID: 0000-0002-6109-8836 and Walkden, Andrew ORCID: 0000-0002-9196-6219
(2022) Current Perspectives on Corneal Transplantation. Clinical ophthalmology (Auckland, N.Z.), 16. 631 - 646.

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Disease of the cornea is the third leading cause of blindness worldwide. Corneal graft surgery is one of the most successful forms of solid organ transplantations in humans, with ever-increasing developments in surgical technique. To date, approximately 4504 corneal transplants are performed in the United Kingdom each year. While full thickness transplantation was the most commonly performed keratoplasty over the last few decades, selective lamellar transplantation of the diseased layers of the cornea has been universally adopted. This comprehensive review aims to provide an updated synthesis on different types of corneal transplantations, their treatment outcomes, and the associated complications of each procedure in both adult and paediatric population. In addition, we also present an up-to-date summary of the emerging therapeutic approaches that have the potential to reduce the demand for donor-dependent keratoplasty.

Item Type: Article
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences
Depositing User: Symplectic Admin
Date Deposited: 16 May 2022 12:34
Last Modified: 24 Jun 2022 00:13
DOI: 10.2147/opth.s289359
Open Access URL: