Influence of eye tilt on corneal densitometry

Consejo, Alejandra, Jimenez-Garcia, Marta, Rozema, Jos J and Abass, Ahmed ORCID: 0000-0002-8622-4632 (2022) Influence of eye tilt on corneal densitometry OPHTHALMIC AND PHYSIOLOGICAL OPTICS, 42 (5). pp. 1032-1037. ISSN 0275-5408, 1475-1313

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Abstract

Purpose: To investigate whether Pentacam densitometry readings are affected by corneal tilt. Methods: In a prospective study, the right eyes of 86 healthy participants aged 42.8 ± 20.0 years (range 18–79 years) were imaged using Scheimpflug tomography. Elevation maps were exported to calculate corneal tilt using custom-made software, and densitometry readings were acquired directly from the corneal densitometry analysis add-on to the standard software Oculus Pentacam HR. Simple mediation analysis was applied to study age as a confounding factor in the correlation between corneal tilt and corneal densitometry. Results: Corneal tilt and corneal densitometry are not independent from one another because age is significantly correlated with both corneal tilt (r = 0.50, p < 0.001) and corneal densitometry (r = 0.91, p < 0.001). Only 3.8% of the correlation between tilt and densitometry operates directly, while the remaining 96.2% depends on age. Conclusions: Corneal tilt plays a role in corneal densitometry readings, even though the interaction is strongly influenced by age. Age is a well-known factor in densitometry readings that should be taken into consideration when interpreting Scheimpflug densitometry.

Item Type:	Article
Uncontrolled Keywords:	cornea, corneal tilt, corneal transparency, densitometry, Pentacam
Divisions:	Faculty of Science & Engineering > School of Engineering
Depositing User:	Symplectic Admin
Date Deposited:	24 May 2022 10:47
Last Modified:	23 May 2026 06:44
DOI:	10.1111/opo.13020
Open Access URL:	https://onlinelibrary.wiley.com/doi/10.1111/opo.13...
Related Websites:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3155399
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