Development of a core outcome set for the orthopaedic management of spinal dysraphism : a study protocol.



Leo, Donato G, Green, Gemma, Eastwood, Deborah M, Bridgens, Anna and Gelfer, Yael
(2022) Development of a core outcome set for the orthopaedic management of spinal dysraphism : a study protocol. Bone & joint open, 3 (1). pp. 54-60.

[thumbnail of Development of a core outcome set for the orthopaedic management of spinal dysraphism  a study protocol.pdf] PDF
Development of a core outcome set for the orthopaedic management of spinal dysraphism a study protocol.pdf - Unspecified

Download (243kB) | Preview

Abstract

<h4>Aims</h4>The aim of this study is to define a core outcome set (COS) to allow consistency in outcome reporting amongst studies investigating the management of orthopaedic treatment in children with spinal dysraphism (SD).<h4>Methods</h4>Relevant outcomes will be identified in a four-stage process from both the literature and key stakeholders (patients, their families, and clinical professionals). Previous outcomes used in clinical studies will be identified through a systematic review of the literature, and each outcome will be assigned to one of the five core areas, defined by the Outcome Measures in Rheumatoid Arthritis Clinical Trials (OMERACT). Additional possible outcomes will be identified through consultation with patients affected by SD and their families.<h4>Results</h4>Outcomes identified in these stages will be included in a two-round Delphi process that will involve key stakeholders in the management of SD. A final list including the identified outcomes will then be summarized in a consensus meeting attended by representatives of the key stakeholders groups.<h4>Conclusion</h4>The best approach to provision of orthopaedic care in patients with SD is yet to be decided. The reporting of different outcomes to define success among studies, often based on personal preferences and local culture, has made it difficult to compare the effect of treatments for this condition. The development of a COS for orthopaedic management in SD will enable meaningful reporting and facilitate comparisons in future clinical trials, thereby assisting complex decision-making in the clinical management of these children. Cite this article: <i>Bone Jt Open</i> 2022;3(1):54-60.

Item Type: Article
Uncontrolled Keywords: Delphi process, Rheumatoid Arthritis, clinical studies, comorbidities, core outcome set, healthcare professionals, lesions, musculoskeletal problems, myelomeningocele, orthopaedic, orthopaedic treatment, physiotherapists, spina bifida, spinal dysraphism
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences
Depositing User: Symplectic Admin
Date Deposited: 21 Oct 2022 08:41
Last Modified: 15 Mar 2024 17:57
DOI: 10.1302/2633-1462.31.bjo-2021-0157.r1
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3165676